Aortic stenosis: even mild disease is significant

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Aortic stenosis: even mild disease is significant.

The spectrum of calcific aortic valve disease ranges from aortic sclerosis, without obstruction to ventricular outflow, to severe aortic stenosis. The natural history of symptomatic and asymptomatic severe aortic valve stenosis has been evaluated by Doppler echocardiography in several retrospective and prospective studies. In addition, there is substantial data on the rate of haemodynamic progr...

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Is aortic stenosis a preventable disease?

Aortic stenosis (AS) is the most common valvular disease requiring valve replacement. Its prevalence increases with age. When the severity of AS is only mild to moderate, it is well tolerated. When it becomes severe, AS confers significant morbidity and mortality. Adverse events can be avoided if it is possible to prevent or retard the progression from mild or moderate AS to severe AS. Progress...

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Aortic Stenosis: Changing Disease Concepts

Aortic stenosis (AS) occurs in almost 10% of adults over age 80 years with a mortality about 50% at 2 years unless outflow obstruction is relieved by aortic valve replacement (AVR). Development of AS is associated with anatomic, clinical and genetic risk factors including a bicuspid valve in 50%; clinical factors that include older age, hypertension, smoking, diabetes and elevated serum lipopro...

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Use of transesophageal echocardiography to predict significant coronary artery disease in aortic stenosis.

STUDY OBJECTIVES This study was conducted to examine if the use of multiplane transesophageal echocardiography (TEE) could predict the absence or the presence of significant coronary artery disease (CAD) in patients with aortic stenosis. DESIGN Prospective study. SETTING University hospital. PATIENTS Clinical, angiographic features and TEE findings were prospectively analyzed in 132 conse...

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Predictors of Echocardiographic Progression in Patients With Mild Aortic Stenosis

BACKGROUND AND OBJECTIVES The factors related to the progression of mild aortic stenosis (AS) remain unknown. We wanted to evaluate the long-term outcomes and predictors of echocardiographic progression in patients with mild AS. SUBJECTS AND METHODS We prospectively included 103 consecutive asymptomatic patients (62.1±11.9 years, 31 males) with mild AS. Mild AS was defined as aortic valve (AV...

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ژورنال

عنوان ژورنال: European Heart Journal

سال: 2004

ISSN: 0195-668X

DOI: 10.1016/j.ehj.2003.12.010